The Technology

GentaGel delivers localized and sustained doses of antibiotics with minimized systemic exposure. The local injection facilitates a higher local dose with expected reduced systemic toxicity, and a slow, prolonged release that will enable treatment exposure to the infection over a longer period, replacing the multiple injections given today, while achieving optimal therapeutic concentrations at the site of infection.

The technology is based on a safe, biodegradable novel polymer which physically incorporate the active drug in its matrix. This allows high drug loads for high API concentrations with relatively low injected volume, while the polymer protects the active ingredients from fast metabolism and excretion. As the polymer degrades, it releases the antibiotics locally, while its biohydrolysis products are fatty acids- which are safe and commonly found in the body.