Injectable, biodegradable local sustained release of antibiotics for prevention & treatment of infections
The Problem
- Local internal infections, are a source of severe complications
- Infections can result in delayed healing & medical problems, leading to increased healthcare costs
- Antibiotics are usually administered systemically, and not directly to the anatomical site of infection
- Extended antibiotic use leads to many toxic side effects
The Need
- Prevent infections rates & related complications
- Overcome the toxic effect of antibiotics
- Treat the infection locally and specifically
Learn more about our solution
Market Insights
Surgical Site Infections (SSI)
The most common hospital-acquired infections
SSI average time and care cost
9.7 days of hospital stay and $20,842 per admission
Annual estimated SSI cases in the US
300,000 cases with annual cost of $10B
Sales of SSI prevention products
Expected to exceed $5.5B in 2023
OUR SOLUTION
GentaGel, a local slow-release antibiotic treatment is injected and continuously releases antibiotics (e.g., Gentamicin) for up to 60 days.
The antibiotic is not detectable in circulation but achieves sufficient therapeutic concentrations in the administered area.
GentaGel assists patients, doctors and the entire healthcare system
Patients
- Single treatment
- Long term effect
- Reduces probability for severe complications
Doctors
- Does not require staff training
- Injected directly & specifically to the surgery area
- Long term treatment by slow- release Health System
Health System
- Less post-operative complications
- Shorter hospitalization time
- Decreased health care costs
GentaGel's Inventor and Co-Founder
Prof. Avi Domb
Currently is the Chief Scientist Ministry of Science and Technology of Israel.
B.Sc degrees in Chemistry (Bar Ilan, 1978), Pharmacy (Hebrew Universiry, 1984) and Law (Hebrew University, 2007). Diploma in Polymer and Textile Chemistry (Hebrew Universiry, 1980), Executive business management (Hebrew Universiry, 1997) and a Ph.D. in Organic Chemistry (Hebrew Universiry, 1985). Postdoctoral Fellowship at Syntex Reseach (1984-5), Harvard Medical School Department of Surgery in the Children’s hospital (1985-6) and Department of Chemical Engineering, M.I.T (1986-7).
